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1

Regorafenib dose-optimisation in patients with refractory metastatic colorectal cancer (ReDOS): a randomised, multicentre, open-label, phase 2 study

Bekaii-Saab, Tanios S, Ou, Fang-Shu, Ahn, Daniel H, Boland, Patrick M, Ciombor, Kristen K, Heying, Erica N, Dockter, Travis J, Jacobs, Nisha L, Pasche, Boris C, Cleary, James M, Meyers, Jeffrey P, Des

Journal:

The Lancet Oncology

Year:

2019

Language:

english

File:

PDF, 1.31 MB

english, 2019

2

A dose-finding, pharmacokinetic and pharmacodynamic study of a novel schedule of flavopiridol in patients with advanced solid tumors

Bhuvaneswari Ramaswamy, Mitch A. Phelps, Robert Baiocchi, Tanios Bekaii-Saab, Wenjun Ni, Ju-Ping Lai, Anna Wolfson, Mark E. Lustberg, Lai Wei, Deidre Wilkins, Angela Campbell, Daria Arbogast, Austin D

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 181 KB

english, 2012

3

Warfarin-induced allergic interstitial nephritis and leucocytoclastic vasculitis

K. G. Kapoor, T. Bekaii-Saab

Journal:

Internal Medicine Journal

Year:

2008

Language:

english

File:

PDF, 85 KB

english, 2008

4

Late Relapse of Ovarian Dysgerminoma: Case Report and Literature Review

Tanios Bekaii-Saab, Lawrence H. Einhorn, Stephen D. Williams

Journal:

Gynecologic Oncology

Year:

1999

Language:

english

File:

PDF, 21 KB

english, 1999

5

Cost description of chemotherapy regimens for the treatment of metastatic pancreas cancer

Goldstein, Daniel A., Krishna, Kavya, Flowers, Christopher R., El-Rayes, Bassel F., Bekaii-Saab, Tanios, Noonan, Anne M.

Journal:

Medical Oncology

Year:

2016

Language:

english

File:

PDF, 489 KB

english, 2016

6

Incidence and Survival of Appendiceal Mucinous Neoplasms

Shaib, Walid L., Goodman, Michael, Chen, Zhengjia, Kim, Sungjin, Brutcher, Edith, Bekaii-Saab, Tanios, El-Rayes, Bassel F.

Journal:

American Journal of Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 140 KB

english, 2015

7

Current and Emerging Therapies in Pancreatic Cancer || Pancreatic Cancer Epidemiology and Environmental Risk Factors

Bekaii-Saab, Tanios, El-Rayes, Bassel

Year:

2018

Language:

english

File:

PDF, 313 KB

english, 2018

8

O-014Regorafenib Dose Optimization Study (ReDOS): Randomized phase II trial to evaluate escalating dosing strategy and pre-emptive topical steroids for regorafenib in refractory metastatic colorectal cancer (mCRC) – An ACCRU Network study

Bekaii-Saab, T, Ou, F, Anderson, D, Ahn, D, Boland, P, Ciombor, K, Jacobs, N, Desnoyers, R, Cleary, J, Meyers, J, Chiorean, E, Pedersen, K, Barzi, A, Sloan, J, McCune, J, Lacouture, M, Lenz, H, Grothe

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 43 KB

english, 2018

9

Clinical update on K-Ras targeted therapy in gastrointestinal cancers

Pant, Shubham, Hubbard, Joleen, Martinelli, Erika, Bekaii-Saab, Tanios

Journal:

Critical Reviews in Oncology/Hematology

Year:

2018

Language:

english

File:

PDF, 692 KB

english, 2018

10

CanStem111P trial: a Phase III study of napabucasin plus nab-paclitaxel with gemcitabine

Sonbol, Mohamad Bassam, Ahn, Daniel H, Goldstein, David, Okusaka, Takuji, Tabernero, Josep, Macarulla, Teresa, Reni, Michele, Li, Chung-Pin, O'Neil, Bert, Cutsem, Eric Van, Bekaii-Saab, Tanios

Journal:

Future Oncology

Year:

2019

File:

PDF, 3.75 MB

2019

11

Assessment of Treatment With Sorafenib Plus Doxorubicin vs Sorafenib Alone in Patients With Advanced Hepatocellular Carcinoma

Abou-Alfa, Ghassan K., Shi, Qian, Knox, Jennifer J., Kaubisch, Andreas, Niedzwiecki, Donna, Posey, James, Tan, Benjamin R., Kavan, Petr, Goel, Rakesh, Lammers, Philip E., Bekaii-Saab, Tanios S., Tam,

Journal:

Year:

2019

Language:

english

File:

PDF, 293 KB

english, 2019

12

Interactions of tamoxifen, N-desmethyltamoxifen and 4-hydroxytamoxifen with P-glycoprotein and CYP3A

Tanios S. Bekaii-Saab, Michael D. Perloff, James L. Weemhoff, David J. Greenblatt, Lisa L. von Moltke

Journal:

Biopharmaceutics & Drug Disposition

Year:

2004

Language:

english

File:

PDF, 138 KB

english, 2004

13

Incorporation of photodynamic therapy as an induction modality in non-small cell lung cancer

Patrick Ross Jr., John Grecula, Tanios Bekaii-Saab, Miguel Villalona-Calero, Gregory Otterson, Cynthia Magro

Journal:

Lasers in Surgery and Medicine

Year:

2006

Language:

english

File:

PDF, 273 KB

english, 2006

14

A Structurally Optimized Celecoxib Derivative Inhibits Human Pancreatic Cancer Cell Growth

Junan Li, Jiuxiang Zhu, W. Scott Melvin, Tanios S. Bekaii-Saab, Ching-Shih Chen, Peter Muscarella

Journal:

Journal of Gastrointestinal Surgery

Year:

2006

Language:

english

File:

PDF, 279 KB

english, 2006

15

Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4+T cells from patients with GI malignancy

Bethany L. Mundy-Bosse, Gregory S. Young, Todd Bauer, Elaine Binkley, Mark Bloomston, Matthew A. Bill, Tanios Bekaii-Saab, William E. Carson, Gregory B. Lesinski

Journal:

Cancer Immunology, Immunotherapy

Year:

2011

Language:

english

File:

PDF, 430 KB

english, 2011

16

Capped-dose mitomycin C: a pooled safety analysis from three prospective clinical trials

Nse Ntukidem, Carlos Arce-Lara, Gregory A. Otterson, Eric Kraut, Spero Cataland, Tanios Bekaii-Saab

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 247 KB

english, 2010

17

A phase I dose escalation study of a pharmacobiologically based scheduling of capecitabine and mitomycin C in patients with gastrointestinal malignancies

Tanios Bekaii-Saab, Marisa Hill, Angela Campbell, Kavitha Kosuri, James Thomas, Miguel Villalona-Calero

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 271 KB

english, 2010

18

A dose-finding and pharmacodynamic study of bortezomib in combination with weekly paclitaxel in patients with advanced solid tumors

Bhuvaneswari Ramaswamy, Tanios Bekaii-Saab, Larry J. Schaaf, Gregory B. Lesinski, David M. Lucas, Donn C. Young, Amy S. Ruppert, John C. Byrd, Kristy Culler, Diedre Wilkins, John J. Wright, Michael R.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 224 KB

english, 2010

19

Phase I trial of non-cytotoxic suramin as a modulator of docetaxel and gemcitabine therapy in previously treated patients with non-small cell lung cancer

Elaine T. Lam, Jessie L.- S. Au, Gregory A. Otterson, M. Guillaume Wientjes, Ling Chen, Tong Shen, Yong Wei, Xiaobai Li, Tanios Bekaii-Saab, Anthony J. Murgo, Rhonda R. Jensen, Michael Grever, Miguel

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 422 KB

english, 2010

20

A phase I study of the biomodulation of capecitabine by docetaxel and gemcitabine (mGTX) in previously untreated patients with metastatic adenocarcinoma of the pancreas

Marisa E. Hill, Xiaobai Li, Sharon Kim, Angela Campbell, Kristy Culler, Mark Bloomston, Mark Zalupski, Gwen Hejna, Tanios Bekaii-Saab

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 266 KB

english, 2011

21

A phase II study of chloroquinoxaline sulfonamide (CQS) in patients with metastatic colorectal carcinoma (MCRC)

Tanios S. Bekaii-Saab, Amir Mortazavi, Lee G. Hicks, Mark Zalupski, Robert J. Pelley, Kenneth K. Chan, Eric H. Kraut

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 206 KB

english, 2006

22

Phase II trial of pyrazoloacridine (NSC#366140) in patients with metastatic breast cancer

Bhuvaneswari Ramaswamy, Ewa Mrozek, John Philip Kuebler, Tanios Bekaii-Saab, Eric H. Kraut

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 107 KB

english, 2011

23

A phase I study of topotecan and gemcitabine in advanced solid tumors

Derek S. Serna, Tanios Bekaii-Saab, Eric H. Kraut

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 105 KB

english, 2011

24

Influence of KRAS mutation status in metachronous and synchronous metastatic colorectal adenocarcinoma

Jeffrey S. Rose, Derek S. Serna, Ludmila Katherine Martin, Xiaobai Li, Lynn M. Weatherby, Sherif Abdel-Misih, Weiqiang Zhao, Tanios Bekaii-Saab

Journal:

Year:

2012

Language:

english

File:

PDF, 346 KB

english, 2012

25

Fractionated radioimmunotherapy with 90Y-clivatuzumab tetraxetan and low-dose gemcitabine is active in advanced pancreatic cancer : A phase 1 trial

Allyson J. Ocean, Kenneth L. Pennington, Michael J. Guarino, Arif Sheikh, Tanios Bekaii-Saab, Aldo N. Serafini, Daniel Lee, Max W. Sung, Seza A. Gulec, Stanley J. Goldsmith, Timothy Manzone, Michael H

Journal:

Year:

2012

Language:

english

File:

PDF, 995 KB

english, 2012

26

Carbohydrate antigen 19-9 is a prognostic and predictive biomarker in patients with advanced pancreatic cancer who receive gemcitabine-containing chemotherapy : A pooled analysis of 6 prospective trials

Todd M. Bauer, Bassel F. El-Rayes, Xiaobai Li, Nazik Hammad, Philip A. Philip, Anthony F. Shields, Mark M. Zalupski, Tanios Bekaii-Saab

Journal:

Year:

2012

Language:

english

File:

PDF, 327 KB

english, 2012

27

Preclinical Experience With Docetaxel in Gastrointestinal Cancers

Tanios S. Bekaii-Saab, Miguel A. Villalona-Calero

Journal:

Seminars in Oncology

Year:

2005

Language:

english

File:

PDF, 211 KB

english, 2005

28

A novel mutation in the tyrosine kinase domain ofERBB2in hepatocellular carcinoma

Tanios Bekaii-Saab, Nita Williams, Christoph Plass, Miguel Villalona Calero, Charis Eng

Journal:

Year:

2006

Language:

english

File:

PDF, 297 KB

english, 2006

29

STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH+/CD133+ stem cell-like human colon cancer cells

Li Lin, James Fuchs, Chenglong Li, Veronica Olson, Tanios Bekaii-Saab, Jiayuh Lin

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 727 KB

english, 2011

30

Treatment Patterns and Clinical Outcomes in Patients With Metastatic Colorectal Cancer Initially Treated with FOLFOX-Bevacizumab or FOLFIRI-Bevacizumab: Results From ARIES, a Bevacizumab Observational Cohort Study

Bendell, J. C., Bekaii-Saab, T. S., Cohn, A. L., Hurwitz, H. I., Kozloff, M., Tezcan, H., Roach, N., Mun, Y., Fish, S., Flick, E. D., Dalal, D., Grothey, A.

Journal:

Year:

2012

Language:

english

File:

PDF, 495 KB

english, 2012

31

O-309 Photodynamic therapy (PDT) can be incorporated into the multimodality treatment of loco-regionally advanced non-small cell lung cancer (NSCLC) with obstructive lesions

Bekaii-Saab, Tanios S., Lavelle, Joseph W., Grainger, Andrew V., Rothrauff, Susan, Villalona-Calero, Miguel A., Otterson, Gregory A., Ross, Patrick

Journal:

Year:

2003

Language:

english

File:

PDF, 181 KB

english, 2003

32

Adjuvant Therapy Following Curative Resection of Metastases

Christina Wu, Tanios Bekaii-Saab

Journal:

Current Colorectal Cancer Reports

Year:

2012

Language:

english

File:

PDF, 167 KB

english, 2012

33

Elevated baseline CA19-9 levels correlate with adverse prognosis in patients with early- or advanced-stage pancreas cancer

Ludmila Katherine Martin, Lai Wei, Elizabeth Trolli, Tanios Bekaii-Saab

Journal:

Medical Oncology

Year:

2012

Language:

english

File:

PDF, 244 KB

english, 2012

34

A phase II study of modulated-capecitabine and docetaxel in chemonaive patients with advanced non-small cell lung cancer (NSCLC)

Bertino, Erin M., Bekaii-Saab, Tanios, Fernandez, Soledad, Diasio, Robert B., Karim, Nagla A., Otterson, Gregory A., Villalona-Calero, Miguel A.

Journal:

Year:

2013

Language:

english

File:

PDF, 252 KB

english, 2013

35

427 POSTER Pharmacokinetics (PK) of EZN-2208, a novel anticancer agent, in patients (pts) with advanced malignancies: a phase I dose-escalation study

A. Patnaik, M. Goldston, C. Takimoto, A. Tolcher, K. Papadopoulos, T. Bekaii-Saab, B. Kleiber, F. Gamza, C. Longley, A. Buchbinder

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 87 KB

english, 2008

36

Complete clinical response of metastatic hepatocellular carcinoma to sorafenib in a patient with hemochromatosis: A case report

Brian J So, Tanios Bekaii-Saab, Mark A Bloomston, Tushar Patel

Journal:

Journal of Hematology & Oncology

Year:

2008

Language:

english

File:

PDF, 251 KB

english, 2008

37

KRAS Testing in Metastatic Colorectal Cancer: Implications on the Use of Biologic Agents

Tanios Bekaii-Saab

Journal:

Clinical Colorectal Cancer

Year:

2009

Language:

english

File:

PDF, 118 KB

english, 2009

38

Yttrium-90 Radioembolization as Salvage Therapy for Colorectal Cancer With Liver Metastases

Martin, Ludmila Katherine, Cucci, Anthony, Wei, Lai, Rose, Jeffrey, Blazer, Marlo, Schmidt, Carl, Khabiri, Hooman, Bloomston, Mark, Bekaii-Saab, Tanios

Journal:

Clinical Colorectal Cancer

Year:

2012

Language:

english

File:

PDF, 305 KB

english, 2012

39

A multi-institutional phase 2 study of neoadjuvant gemcitabine and oxaliplatin with radiation therapy in patients with pancreatic cancer

Kim, Edward J., Ben-Josef, Edgar, Herman, Joseph M., Bekaii-Saab, Tanios, Dawson, Laura A., Griffith, Kent A., Francis, Isaac R., Greenson, Joel K., Simeone, Diane M., Lawrence, Theodore S., Laheru, D

Journal:

Year:

2013

Language:

english

File:

PDF, 316 KB

english, 2013

40

Antiemetic Control with Palonosetron in Patients with Gastrointestinal Cancer Receiving a Fluoropyrimidine-Based Regimen in Addition to Either Irinotecan or Oxaliplatin: A Retrospective Study

Blazer, Marlo, Phillips, Gary, Reardon, Joshua, Efries, David, Smith, Yahna, Weatherby, Lynn, Juergens, Kim, Rose, Jeffrey, Griffith, Niesha, Bekaii-Saab, Tanios

Journal:

Year:

2012

Language:

english

File:

PDF, 333 KB

english, 2012

41

Photodynamic Therapy (PDT) May Provide Effective Palliation in the Treatment of Primary Tracheal Carcinoma: A Small Case Series

Martin, Ludmila Katherine, Otterson, Gregory A., Bekaii-Saab, Tanios

Journal:

Photomedicine and Laser Surgery

Year:

2012

Language:

english

File:

PDF, 99 KB

english, 2012

42

Peptide Vaccines and Peptidomimetics of EGFR (HER-1) Ligand Binding Domain Inhibit Cancer Cell Growth In Vitro and In Vivo

Foy, K. C., Wygle, R. M., Miller, M. J., Overholser, J. P., Bekaii-Saab, T., Kaumaya, P. T. P.

Journal:

The Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 2.77 MB

english, 2013

43

The Addition of Radiation to Chemotherapy does not Improve Outcome When Compared to Chemotherapy in the Treatment of Resected Pancreas Cancer: The Results of a Single-Institution Experience

Martin, Ludmila Katherine, Luu, Dai Chu, Li, Xiaobai, Muscarella, Peter, Christopher Ellison, E., Bloomston, Mark, Bekaii-Saab, Tanios

Journal:

Annals of Surgical Oncology

Year:

2014

Language:

english

File:

PDF, 302 KB

english, 2014

44

Safety and Effectiveness of Bevacizumab Treatment for Metastatic Colorectal Cancer: Final Results from the Avastin® Registry – Investigation of Effectiveness and Safety (ARIES) Observational Cohort Study

Hurwitz, H.I., Bekaii-Saab, T.S., Bendell, J.C., Cohn, A.L., Kozloff, M., Roach, N., Mun, Y., Fish, S., Flick, E.D., Grothey, A.

Journal:

Clinical Oncology

Year:

2014

Language:

english

File:

PDF, 495 KB

english, 2014

45

P-692 Photodynamic therapy (PDT) for primary tracheal carcinoma

Bekaii-Saab, Tanios S., Grainger, Andrew V., Lavelle, Joseph W., Rothrauff, Susan, Ross, Patrick, Otterson, Gregory A.

Journal:

Year:

2003

Language:

english

File:

PDF, 364 KB

english, 2003

46

6604 Exploring the role of CA 19–9 level as a predictor of survival in patients with advanced pancreatic adenocarcinoma

Bekaii-Saab, T., Majumber, A., Trolli, E., Thomas, J.

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

47

Prolonging Surgical Resection After Neoadjuvant Chemoradiation for Rectal Cancer Is Associated With Increased Risk of Distant Failure and Decreased Survival

Nguyen, P., Wuthrick, E., Robinson, A., Chablani, P., Wu, C., Bekaii-Saab, T., Williams, T.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2013

Language:

english

File:

PDF, 43 KB

english, 2013

48

Trends in Intensity Modulated Radiation Therapy Use for Locally-Advanced Rectal Cancer at National Comprehensive Cancer Network (NCCN) Centers

Laufer, M., A. ter Veer,, Bekaii-Saab, T., Engstrom, P.F., Lai, L., Schrag, D., Skibber, J.M., Small, W., Wilkinson, N., Goodman, K.A.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2013

Language:

english

File:

PDF, 45 KB

english, 2013

49

Tu1912 Determining Novel Clinicopathologic Correlations of High Grade Pancreatic Intraepithelial Neoplasia (PanIN) in Pancreatic Ductal Adenocarcinoma (PDAC)

Park, Jean R., Li, Feng, Wellner, Michael, Thomas, Jordan, Sklaw, Brett C., Sklaw, Brett C., Cronley, Kevin M., Oza, Veeral, Grewal, Jasleen, Groce, Jeffery R., Swanson, Benjamin, Bekaii-Saab, Tanios,

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 392 KB

english, 2014

50

Sa1370 Pancreatic Intraepithelial Neoplasia in Resected Pancreatic Lesions: Prevalence, Significance and Implications

Li, Feng, Park, Jean R., Wellner, Michael, Thomas, Jordan, Sklaw, Brett C., Cronley, Kevin M., Oza, Veeral, El-Dika, Samer, Swanson, Benjamin, Bekaii-Saab, Tanios, Conwell, Darwin, Krishna, Somashekar

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 859 KB

english, 2014

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